Alcohol metabolism and why a few drinks linger longer than you think Your body processes >90% of ethanol in the liver, but the path creates toxic byproducts and drains key cofactors. 1 Pathophysiological Aspects of Alcohol Metabolism in the Liver An Inverse Electron Demand DielsAlder Approach to Selective Activity Based Sensing of Acetaldehyde in Living Cells Journal of the American Chemical Society The science behind hangovers The site of detoxification in your body is located in your liver. Everything that you ingest is broken down in your digestive system to become small enough Detox from the harmful effects of alcohol ! Therascience Pathophysiological Aspects of Alcohol Metabolism in the Liver